淋巴細胞抗原Ly6D抗體,Anti-LY6D抗體 返回列表頁

背景介紹：Ly-6D is a 128 amino acid glycoprotein that is expressed in squamous cell carcinoma cell lines and squamous cell epithelia tissue. Ly-6D contains a signal peptide, 2 theoretical phosphorylation sites and 3 putative myristoylation sites. Upregulation of the gene encoding Ly-6D in head and neck cancers is associated with poor prognosis and high expression of Ly-6D has been linked to enhanced cell migration. Ly-6D is frequently used as a molecular marker for diagnosis and therapy of head-and-neck squamous cell carcinoma (HNSCC). It has been suggested that Ly-6D may regulate the expression levels of certain fucosylated E-selectin ligands and protein FX, a protein that contributes to the last step in the synthesis of GDP-L-fucose, in HNSCC cell lines. This finding is indicative that Ly-6D may regulate tumor cell adhesion in inflamed vessel walls that express E-selectin.

別名：E48 antigen; LY 6D; LY-6D;Lymphocyte antigen 6 complex; LY6D_HUMAN; Lymphocyte antigen 6 complex locus D; Lymphocyte antigen D; Lymphocyte antigen 6D. 

淋巴細胞抗原Ly6D抗體,Anti-LY6D抗體簡單介紹：

產(chǎn)品編號：BYK-18604R

英文名稱：Anti-LY6D
中文名稱：淋巴細胞抗原Ly6D抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請或添加客服直接索取）

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

淋巴細胞抗原Ly6D抗體,Anti-LY6D抗體產(chǎn)品信息：

免疫組化問題解答

染色過強？

原因：抗體濃度過高或孵育時間過長

解決方法：降低抗體滴度、抗體孵育時間：室溫1小時或4度過夜

原因：孵育溫度過高超過37度:

解決方法：一般在室溫20-28度

原因：DAB顯色時間過長或濃度過高?

解決方法：顯色時間不超過5-12分鐘，以顯微鏡下觀察為準

非特異性背景染色？

原因：操作過程中沖洗不充分

解決方法：每步?jīng)_洗3次每次5分鐘

原因：組織中含過氧化物酶未阻斷 

解決方法：可再配置新鮮3%H2O2封閉孵育時間延長 

原因：組織中含內(nèi)原性* 

解決方法：正常非免疫動物血清再封閉

原因：血清蛋白封閉不充分 

解決方法：血清蛋白封閉不充分

淋巴細胞抗原Ly6D抗體,Anti-LY6D抗體相關(guān)產(chǎn)品：

Anti-SDH/S6PDH 6-磷酸*脫氫酶抗體
Anti-GPR147/NPFF1 Receptor G蛋白偶聯(lián)受體147抗體
Anti-SP-C Propeptide 肺表面活性蛋白C前體肽抗體
Anti-Runx3 Runx3抗體
Anti-Syntenin 1 多配體聚糖結(jié)合蛋白1抗體
Anti-RXR Alpha/RXRA/Retinoid X receptor 核受體RXRα抗體
Anti-RRAD RRAD抗體
Anti-phospho-PIK3 gamma(Thr1024) 磷酸化磷脂酰肌醇激酶PIK3-γ抗體
Anti-phospho-Rb/p105-Rb(Ser780) 磷酸化成視網(wǎng)膜細胞瘤抑癌蛋白抗體
Anti-GRID2IP *受體δ2/GluR-δ2抗體
Anti-ROS/c ros  活性氧簇ROS抗體
Anti-AOA1/Aprataxin 共濟失調(diào)性眼球運動功能喪失相關(guān)蛋白AOA1抗體
Anti-RPLP0  酸性核糖體磷蛋白大亞基P0抗體
Anti-METRN Meteorin神經(jīng)膠質(zhì)細胞分化調(diào)節(jié)蛋白抗體
Anti-ROCK2 Rho相關(guān)蛋白激酶2抗體